Publications

Books

Research Papers

2010-Current

Richards, T.A., Soanes, D.M., Jones, M.D., Vasieva, O., Leonard, G., Paszkiewicz, K., Foster, P.G., Hall, N., Talbot, N.J. (2011) Horizontal gene transfer facilitated the evolution of plant parasitic mechanisms in the oomycetes. Proc Natl Acad Sci U S A. Aug 30.

Amselem, J., Cuomo, C.A., van Kan, J.A., Viaud, M., Benito, E.P., Couloux, A. et al. (2011) Genomic analysis of the necrotrophic fungal pathogens Sclerotinia sclerotiorum and Botrytis cinerea. PLoS Genet. 7: e1002230.

Shlezinger, N., Minz, A., Gur, Y., Hatam, I., Dagdas, Y.F., Talbot, N.J., Sharon, A. (2011) Anti-apoptotic machinery protects the necrotrophic fungus Botrytis cinerea from host-induced apoptotic-like cell death during plant infection. PLoS Pathog. 7: e1002185.

Takan, J.P., Chipili, J., Muthumeenakshi, S., Talbot, N.J., Manyasa, E.O., Bandyopadhyay, R., Sere, Y., Nutsugah, S.K., Talhinhas, P., Hossain, M., Brown, A.E., Sreenivasaprasad. S. (2011) Magnaporthe oryzae populations adapted to finger millet and rice exhibit distinctive patterns of genetic diversity, sexuality and host interaction. Mol Biotechnol Jun 24.

Koharudin, L.M., Viscomi, A.R., Montanini, B., Kershaw, M.J., Talbot, N.J., Ottonello, S., Gronenborn, A.M. (2011) Structure-function analysis of a CVNH-LysM lectin expressed during plant infection by the rice blast fungus Magnaporthe oryzae. Structure 19: 662-674.

Leonard, G., Soanes, D.M., Stevens, J.R. (2011) Resolving the question of trypanosome monophyly: A comparative genomics approach using whole genome data sets with low taxon sampling. Infect Genet Evol. 11: 955-959.

Yan, X., Ma, W.B., Li, Y., Wang, H., Que, Y.W., Ma, Z.H., Talbot, N.J., Wang, Z.Y. (2011) A sterol 14a-demethylase is required for conidiation, virulence and for mediating sensitivity to sterol demethylation inhibitors by the rice blast fungus Magnaporthe oryzae. Fungal Genet Biol. 48: 144-153.

Spanu, P.D., Abbott, J.C., Amselem, J., Burgis, T.A., Soanes, D.M., Stüber, K., Ver Loren van Themaat, E. et al. (2010) Genome expansion and gene loss in powdery mildew fungi reveal tradeoffs in extreme parasitism. Science 330: 1543-1546.

Wilson, R.A., Gibson, R.P., Quispe, C.F., Littlechild, J.A., Talbot, N.J. (2010) An NADPH-dependent genetic switch regulates plant infection by the rice blast fungus. Proc Natl Acad Sci U S A. 107: 21902-21907

Soanes, D.M., Talbot, N.J. (2010) Comparative genome analysis reveals an absence of leucine-rich repeat pattern-recognition receptor proteins in the kingdom Fungi. PLoS ONE 5: e12725.

Li, Y., Liang, S., Yan, X., Wang, H., Li, D., Soanes, D.M., Talbot, N.J., Wang, Z., Wang Z. (2010) Characterization of MoLDB1 required for vegetative growth, infection-related morphogenesis, and pathogenicity in the rice blast fungus Magnaporthe oryzae. Mol Plant Microbe Interact. 23: 1260-1274.

Saunders, D.G., Dagdas, Y.F., Talbot, N.J. (2010) Spatial uncoupling of mitosis and cytokinesis during appressorium-mediated plant infection by the rice blast fungus Magnaporthe oryzae. Plant Cell 22: 2417-2428.

Saunders, D.G., Aves, S.J., Talbot, N.J. (2010) Cell cycle-mediated regulation of plant infection by the rice blast fungus. Plant Cell 22: 497-507.

Li, Y., Yan, X., Wang, H., Liang, S., Ma, W.B., Fang, M.Y., Talbot, N.J., Wang, Z.Y. (2010) MoRic8 Is a novel component of G-protein signaling during plant infection by the rice blast fungus Magnaporthe oryzae. Mol Plant Microbe Interact. 23: 317-331.

2005-2009

Kershaw, M.J., Talbot, N.J. (2009) Genome-wide functional analysis reveals that infection-associated fungal autophagy is necessary for rice blast disease. Proc Natl Acad Sci U S A. 106: 15967-15972

Richards, T.A., Soanes, D.M., Foster, P.G., Leonard, G., Thornton, C.R., Talbot, N.J. (2009) Phylogenomic analysis demonstrates a pattern of rare and ancient horizontal gene transfer between plants and fungi. Plant Cell 21: 1897-1911.

Parker, D., Beckmann, M., Zubair, H., Enot D.P., Caracuel-Rios, Z., Overy, D.P., Snowdon, S., Talbot, N.J., Draper, J. (2009) Metabolomic analysis reveals a common pattern of metabolic re-programming during invasion of 3 host plant species by Magnaporthe grisea. Plant J. 59: 723-737

Soanes, D.M., Alam, I., Cornell, M.J., Wong, H.M., Hedeler, C., Paton, N.W., Rattray, M., Hubbard, S.J., Oliver, S.G., Talbot, N.J. (2008) Comparative genome analysis of filamentous fungi reveals gene family expansions associated with fungal pathogenesis. PLoS ONE 3: e2300.

Parker, D., Beckmann, M., Enot, D.P., Overy, D.P., Caracuel-Rios, Z., Gilbert, M., Talbot, N.J., Draper, J. (2008) Rice blast infection of Brachypodium distachyon as a model system to study dynamic host/pathogen interactions. Nature Protocols 3: 435-445.

Hedeler, C., Wong, H.M., Cornell, M.J., Alam, I., Soanes, D.M., Rattray, M., Hubbard, S.J., Talbot, N.J., Oliver, S.G., Paton, N.W. (2007) e-Fungi: a data resource for comparative analysis of fungal genomes. BMC Genomics 8: 426.

Cornell, M.J., Alam, I., Soanes, D.M., Wong, H.M., Hedeler, C., Paton, N.W., Rattray, M., Hubbard, S.J., Talbot, N.J., Oliver, S.G. (2007) Comparative genome analysis across a kingdom of eukaryotic organisms: Specialization and diversification in the Fungi. Genome Res. 17: 1809-1822.

Alam, I., Cornell, M.J., Soanes, D.M., Hedeler, C., Wong, H.M., Rattray, M., Hubbard, S.J., Talbot, N.J., Oliver, S.G., Paton, N.W. (2007) A Methodology for Comparative Functional Genomics. Journal of Integrative Bioinformatics 4: 69.

Wilson, R.A., Jenkinson, J.M., Gibson R.P., Littlechild, J.A., Wang Z., Talbot, N.J. (2007) Tps1 regulates the pentose phosphate pathway, nitrogen metabolism and fungal virulence. EMBO Journal 26: 3673-3685.

Egan, M.J., Wang, Z-Y., Jones, M.A., Smirnoff, N., Talbot, N.J. (2007) Generation of reactive oxygen species by fungal NADPH oxidases is required for rice blast disease. Proc. Natl. Acad. Sci. USA 104: 11772-11777.

Richards, T.A., Talbot, N.J. (2007) Plant parasitic oomycetes such as phytophthora species contain genes derived from three eukaryotic lineages. Plant Signaling & Behavior 2: 112–114.

Wang, Z-Y, Soanes, D. M., Kershaw, M.J., and Talbot, N.J. (2007) Functional analysis of lipid metabolism in Magnaporthe grisea reveals a requirement for peroxisomal fatty acid ß-Oxidation during appressorium-mediated plant infection. Molecular Plant-Microbe Interactions 20: 475–491.

Veneault-Fourrey, Talbot, N.J. (2007) Autophagic cell death and its importance for fungal developmental biology and pathogenesis. Autophagy 3: 126-127.

Thornton, C.R., Talbot, N.J. (2006) Immunofluorescence microscopy and immunogold EM for investigating fungal infection of plants. Nature Protocols 1: 2506-2511.

Richards, T.A., Dacks, J.B., Jenkinson, J.M., Thornton, C.R., Talbot, N.J. (2006) Evolution of filamentous plant pathogens: Gene exchange across Eukaryotic kingdoms. Current Biology 16: 1857-1864.

Bhambra, G.K., Wang, Z-Y., Soanes, D.M., Wakley G.E., Talbot, N.J. (2006) Peroxisomal carnitine acetyl transferase is required for elaboration of penetration hyphae during plant infection by Magnaporthe grisea. Molecular Microbiology 61: 46-60.

Gilbert, M.J., Thornton, C.R., Wakley, G.E., Talbot, N.J. (2006) A P-type ATPase required for rice blast disease and induction of host resistance. Nature 440: 535-539.

Veneault-Fourrey, C., Barooah, M., Egan, M., Wakley, G., Talbot, N.J. (2006) Autophagic fungal cell death is necessary for infection by the rice blast fungus. Science 312: 580-583.

Soanes, D.M., Talbot, N.J. (2006) Comparative genomic analysis of phytopathogenic fungi using expressed sequence tag (EST) collections. Molecular Plant Pathology 7: 61-70.

Dean, R.A., Talbot, N.J., Ebbole, D.J., Farman, M.L., et al. (2005) The genome sequence of the rice blast fungus Magnaporthe grisea. Nature 434: 980-986.

Fry, F.H., Okarter, N., Baynton-Smith, C., Kershaw, M.J., Talbot, N.J., Jacob, C. (2005) Use of a substrate/aliinase combination to generate anti-fungal activity in situ. J. Agric Food Chemistry 53: 574-580.

Kershaw, M.J., Thornton, C.R., Wakley, G.E., Talbot, N.J. (2005). Four conserved intra-molecular disulfide linkages are required for secretion and cell wall localisation of a hydrophobin during fungal morphogenesis. Molecular Microbiology 56: 117-125.

Soanes, D.M., Talbot, N.J. (2005) A bioinformatics tool for analysis of EST abundance during infection-related development by Magnaporthe grisea. Molecular Plant Pathology 6: 503-512.

2000-2004

Park, G., Bruno, K.S., Staiger, C.J., Talbot, N.J., Xu, J.R. (2004) Independent genetic mechanisms mediate turgor generation and penetration peg formation during plant infection in the rice blast fungus. Molecular Microbiology 53: 1695-1707.

Routledge, A. P. M., Shelley, G., Smith, J.V., Talbot, N.J., Draper, J., Mur, L.A.J. (2004) Magnaporthe grisea interactions with the model grass Brachypodium distachyon closely resemble those with rice (Oryza sativa). Molecular Plant Pathology 5: 253-265.

Seymour, F.A., Cresswell, J.E., Fisher, P.J., Lappin-Scott, H.M., Haag, H., Talbot, N.J. (2004) The influence of genotypic variation on metabolite diversity in populations of two endophytic fungal species. Fungal Genetics and Biology 41: 721-734.

Tucker, S.L. Thornton, C.R., Tasker, K., Jacob, C., Giles, G., Egan, M., Talbot, N.J. (2004) A fungal metallothionein is required for pathogenicity of Magnaporthe grisea. The Plant Cell 16: 1575-1588.

Whiteford, J.R., Lacroix, H., Talbot, N.J., Spanu, P.D. (2004) Stage-specific cellular localisation of two hydrophobins during plant infection by the pathogenic fungus Cladosporium fulvum Fungal Genetics and Biology 41: 624-634.

Foster, A.J., Jenkinson, J.M., Talbot, N. J. (2003) Trehalose synthesis and metabolism are required at different stages of plant infection by Magnaporthe grisea. EMBO Journal 22: 225-235.

Holcombe, M., Holcombe L, Gheorghe, M, Talbot, N.J. (2003) A hybrid machine model for rice blast fungus Magnaporthe grisea. Biosystems 68: 223-228.

Mey, G., Correia, T., Oeser, B., Kershaw, M.J., Garre, V., Arntz, C. C., Talbot, N.J., Tudzynski, P. (2003) Structural and functional analysis of an oligomeric hydrophobin gene from Claviceps purpurea. Molecular Plant Pathology 4: 31-41.

Wang, Z.Y., Thornton, C.R., Kershaw, M.J., Debao, L., Talbot, N.J. (2003) The glyoxylate cycle is required for temporal regulation of virulence by the plant pathogenic fungus Magnaporthe grisea. Molecular Microbiology 47: 1601-1612.

Soanes, D.M., Kershaw, M.J., Cooley, R.N., Talbot, N.J (2002). Regulation of the MPG1 hydrophobin gene from Magnaporthe grisea. Molecular Plant-Microbe Interactions 15: 1253-1267.

Soanes, D.M., Skinner, W., Keon, J., Hargreaves, J., Talbot, N.J. (2002) Genomics of phytopathogenic fungi and the development of bioinformatic resources. Molecular Plant-Microbe Interactions 15: 421-427.

Thornton C.R., Pitt D., Wakley G.E., Talbot N.J. (2002) Production of a monoclonal antibody specific to the genus Trichoderma and closely related fungi, and its use to detect Trichoderma spp. in naturally infested composts. Microbiology. 148: 1263-79.

Viaud, M., Balhadère, P.V., Talbot, N.J. (2002) A Magnaporthe grisea cyclophilin acts as a virulence determinant during plant infection. The Plant Cell 14: 917-930.

Balhadère, P.V., Talbot, N.J. (2001) PDE1 encodes a P-type ATPase involved in appressorium mediated plant infection by Magnaporthe grisea. The Plant Cell 13: 1987-2004.

Bindslev, L., Kershaw, M.J., Talbot, N.J., and Oliver, R.P. (2001) Complementation of the cAMP-dependent protein kinase A mutant of Magnaporthe grisea by Blumeria graminis PKA-c gene: functional genetic analysis of an obligate biotrophic fungus. Molecular Plant-Microbe Interactions 14: 1368-1375.

1993-1999

Thines, E., Weber, R.W., Talbot, N.J. (2000) MAP kinase and protein kinase A-dependent mobilization of triacylglycerol and glycogen during appressorium turgor generation by Magnaporthe grisea. The Plant Cell 12: 1703-1718.

Balhadère, P.V., Foster, A.J, Talbot N.J. (1999) Identification of pathogenicity mutants of the rice blast fungus Magnaporthe grisea by insertional mutagenesis. Molecular Plant-Microbe Interactions 2: 129-142.

Dixon, K.P., Xu, J.R., Smirnoff, N., Talbot, N.J. (1999) Independent signaling pathways regulate cellular turgor during hyperosmotic stress and appressorium-mediated plant infection by Magnaporthe grisea. The Plant Cell. 11: 2045-2058.

Kershaw, M.J., Wakley, G., Talbot, N.J. (1998) Complementation of the mpg1 mutant phenotype in Magnaporthe grisea reveals functional relationships between fungal hydrophobins. EMBO Journal 17: 3838-3849.

McCafferty, H.R., Talbot, N.J. (1998) Identification of three ubiquitin genes of the rice blast fungus Magnaporthe grisea, one of which is highly expressed during initial stages of plant colonisation. Current Genetics 33: 352-361.

de Jong, J.C, McCormack, B.J., Smirnoff, N., Talbot, N.J. (1997) Glycerol generates turgor in rice blast. Nature 389: 244-245.

Talbot, N.J., Kershaw, M.J., Wakley, G.E., De Vries, O., Wessels, J., Hamer, J.E. (1996) MPG1 encodes a fungal hydrophobin involved in surface interactions during infection-related development of Magnaporthe grisea. The Plant Cell 8: 985-999.

Talbot, N.J., Vincent, P., Wildman, H.G. (1996) The influence of genotype and environment on the physiological and metabolic diversity of Fusarium compactum. Fungal Genetics and Biology 20: 254-267.

Talbot, N.J., Ebbole, D.J., Hamer, J.E. (1993) Identification and characterization of MPG1, a gene involved in pathogenicity from the rice blast fungus Magnaporthe grisea. The Plant Cell 5: 1575-1590.

Talbot, N.J., Salch, Y.P., Ma, M., Hamer, J.E. (1993) Karyotypic variation within clonal lineages of the rice blast fungus, Magnaporthe grisea. Applied and Environmental Microbiology 59: 585-593.

Reviews

2010-Current

Richards, T.A., Leonard, G., Soanes, D.M., Talbot, N.J. (2011) Gene transfer into the fungi. Fungal Biology Reviews 25: 98-110.

Talbot, N.J. (2010) Cell biology: Raiding the sweet shop. Nature 468: 510-511.

Talbot, N.J. (2010) Living the sweet life: how does a plant pathogenic fungus acquire sugar from plants? PLoS Biol. 8: e1000308.

2005-2009

Wilson, R.A., Talbot, N.J. (2009) Fungal physiology - a future perspective. Microbiology 155: 3810-3815.

Talbot, N.J., Kershaw, M.J. (2009) The emerging role of autophagy in plant pathogen attack and host defence. Curr Opin Plant Biol. 12: 444-450.

Rispail N., Soanes D.M., Ant C., Czajkowski R., Grünler A., Huguet R., et al. (2009) Comparative genomics of MAP kinase and calcium–calcineurin signalling components in plant and human pathogenic fungi. Fungal Genetics and Biology 46: 287–298.

Wilson, R.A., Talbot, N.J. (2009) Under pressure: investigating the biology of plant infection by Magnaporthe oryzae. Nature Reviews Microbiology 7: 185-195.

Soanes, D.M., Talbot, N.J. (2008) Moving targets: rapid evolution of oomycete effectors. Trends in Microbiology 16: 507-510.

Egan, M., Talbot, N.J. (2008) Genomes, free radicals and plant cell invasion: recent developments in plant pathogenic fungi. Current Opinion in Plant Biology 11: 367–372.

Caracuel-Rios, Z., Talbot, N.J. (2008) Silencing the crowd: high-throughput functional genomics in Magnaporthe oryzae. Molecular Microbiology 68: 1341-1344.

Soanes, D.M., Richards, T.A., Talbot, N.J. (2007) Insights from sequencing fungal and oomycete genomes: What can we learn about plant disease and the evolution of pathogenicity? Plant Cell 19: 3318-3326.

Talbot, N.J. (2007) Plant pathology: deadly special deliveries. Nature 450: 41-43.

Caracuel-Rios, Z., Talbot, N.J. (2007) Cellular differentiation and host invasion by the rice blast fungus Magnaporthe grisea. Current Opinion in Microbiology 10: 339-345.

Talbot, N.J. (2007) Fungal genomics goes industrial. Nature Biotechnology 25: 542-543.

Wang, Z.Y., Jenkinson, J.M., Holcombe, L.J., Soanes, D.M, Veneault-Fourrey, C., Bhambra, G.K. (2005) The molecular biology of appressorium turgor generation by Magnaporthe grisea. Biochem. Soc. Trans. 33: 384-388.

2000-2004

Elliott, M.A., Talbot, N.J. (2004) Building filaments in the air: the genetics of aerial morphogenesis in bacteria and fungi. Current Opinion in Microbiology 7: 1-8.

Talbot, N.J. (2004) Let there be blight: functional analysis of virulence in Phytophthora infestans. Molecular Microbiology 51: 913-915.

Talbot, N.J. (2003) Aerial morphogenesis: enter the chaplins. Current Biology 13: R696-698.

Talbot, N.J. (2003) Functional genomics of plant-pathogen interactions. New Phytologist 159: 1-4.

Talbot, N.J. (2003) On the trail of a cereal killer: Exploring the biology of Magnaporthe grisea. Annual Review of Microbiology 57: 177-202.

Tunlid, A., Talbot, N.J. (2002) Genomics of parasitic and symbiotic fungi. Current Opinion in Microbiology 5: 513-519.

Tucker, S.L., Talbot, N.J. (2001) Surface attachment and pre-penetration stage development by plant pathogenic fungi. Annual Review of Phytopathology 39: 385-417.

Talbot, N.J., Hamer, L. (2000) Taming the uncultured. Nature Biotechnology 18: 146-7.

1995-1999

Talbot, N.J. (1999) Coming up for air and sporulation. Nature 398: 295-296.

Kershaw, M.J., Talbot, N.J. (1998) Hydrophobins and repellents: proteins with fundamental roles in fungal morphogenesis. Fungal Genetics and Biology 23: 18-33.

Hamer, J.E., Talbot, N.J. (1998) Infection-related development in the rice blast fungus Magnaporthe grisea. Current Opinions in Microbiology. 1: 693-697.

Talbot, N.J. (1997) Growing into the air. Current Biology 7: R78-81.

Talbot, N.J. (1995) Having a blast: exploring the pathogenicity of Magnaporthe grisea. Trends in Microbiology 3: 9-16